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NEOPLASM PROTEINS
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DeCS
Descriptor
English
:
Neoplasm Proteins
Descriptor
Spanish
:
Proteínas de Neoplasias
Descriptor
Portuguese
:
Proteínas de Neoplasias
Tree Number:
D12.776.624
Definition
English
:
Proteins
whose abnormal expression (gain or loss) are associated with the development,
growth
, or progression of
NEOPLASMS
. Some
neoplasm proteins
are tumor
antigens
(
ANTIGENS
, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many
neoplasm proteins
have been characterized and are used as tumor markers (
BIOMARKERS
, TUMOR) when they are detectable in cells and
body fluids
as monitors for the presence or
growth
of tumors. Abnormal expression of
ONCOGENE PROTEINS
is involved in neoplastic transformation, whereas the loss of expression of
TUMOR SUPPRESSOR PROTEINS
is involved with the loss of
growth
control
and progression of the neoplasm.
Indexing Annotation
English
:
IM & coord with specific protein (IM) + specific histol type (IM) + specific organ/neoplasms term (IM); Manual 24.4.4.4
See Related
English
:
Antigens, Neoplasm
Biomarkers, Tumor
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
9556
Unique Identifier:
D009363
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS